KLHL29 (Kelch-like protein 29), also known as KBTBD9, is a 655aa protein that is related to the Drosophila Kelch protein.
Mutations affecting Kelch function result in failure of Kelch to associate with the ring canals and subsequent female sterility.
Human KLHL29 contains six kelch repeats and one BTB (POZ) domain.
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers.
Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function.
KLHL29 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 2p24.1.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human KLHL29. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human KLHL29.
