The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers.
Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function.
The Kelch repeat and BTB domain-containing protein 7 (KBTBD7) contains 1 BTB (POZ) domain and 5 Kelch repeats suggesting a role in transcription regulation.
The gene encoding KBTBD7 maps to chromosome 13, which contains 400 genes including key tumor suppressor genes such as the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:200Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human KBTBD7.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to human KBTBD7.
