84-4389-64　［取扱停止］Inhibin beta-A (Inhibin beta A Chain, Activin beta-A Chain, Erythroid Differentiation Protein, EDF, INHBA, Inhibin Ba, InhibinB A, InhibinB-A 50ul　360560

特徴

• The TGFB superfamily is composed of numerous growth and differentiation factors, including transforming growth factor B (TGFB) 1, 2 and 3; growth/differentiation factor (GDF) 1 through 8; Mullerian inhibiting substance (MIS); bone morphogenic protein (BMP) 2 through 8; glial cell line-derived neurotrophic factor (GDNF); Inhibins (a B-A, B-B and B-C), Lefty and Nodal.
• Members of the TGFB superfamily are involved in embryonic development and adult tissue homeostasis.
• Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.
• Inhibins and activins are involved in regulating a number of functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, Insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
• Activins oppose the funtions of Inhibins.
• Inhibins are predominantly expressed in liver, uterus and ovary tissue.
• Inhibin A, a dimer of a and B-A, and Inhibin B, a dimer of a and B-B, have been shown to inhibit the secretion of follicle stimulating hormone.
• Inhibin B-C forms a homodimer and its expression is predominant in adult liver.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.