84-4389-63　［取扱停止］INHBB (Inhibin beta B Chain, Activin beta-B Chain, INHBB) 100ul　360559

特徴

• The TGFbeta superfamily is composed of numerous growth and differentiation factors, including transforming growth factor beta (TGFbeta) 1, 2 and 3; growth/ differentiation factor (GDF) 1 through 8; Mullerian inhibiting substance (MIS); bone morphogenic protein (BMP) 2 through 8; glialcell line-derived neurotrophic factor (GDNF); Inhibins (alpha, beta-A, beta-B and beta-C), Lefty and Nodal.
• Members of the TGFbeta superfamily are involved in embryonic development and adult tissue homeostasis.
• Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.
• Inhibins and activins are involved in regulating a number of functions such as hypothala mic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, Insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
• Activins oppose the funtions of Inhibins.
• Inhibins are predominantly expressed in liver, uterus and ovary tissue.
• Inhibin A, a dimer of alpha and beta-A, and Inhibin B, a dimer of alpha and beta-B, have been shown to inhibit the secretion of follicle stimulating hormone.
• Inhibin beta-C forms a homodimer and its expression is predominant in adult liver.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.