84-4388-89　［取扱停止］IDH2 (Isocitrate Dehydrogenase [NADP], Mitochondrial, IDH, ICD-M, IDP, NADP(+)-specific ICDH, Oxalosuccinate Decarboxylase) 50ul　360446

特徴

• IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452aa enzyme encoded by the human gene IDH2.
• IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions.
• IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria.
• It is believed to play a role in intermediary metabolism and energy production.
• IDH2 also tightly associates with the pyruvate dehydrogenase complex.
• IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.