84-4388-73　［取扱停止］HSPBAP1 (HSPB1-Associated Protein 1, 27kD Heat Shock Protein-Associated Protein 1, Protein Associated with Small Stress Protein 1, PASS1) 50ul　360437

特徴

• HSPBAP1 (HSPB (heat shock 27kD) associated protein 1), also known as PASS1 (protein associated with small stress protein 1), is a 488aa cytoplasmic protein that contains one JMJC (Jumonji C) domain and shares 80% identity with its rat homolog, PASS1.
• Widely expressed with highest expression in ovary, thymus and pancreas, HSPBAP1 is thought to play a role in mediating cellular stress responses within the cell.
• Due to the presence of a JMJC domain, HSPBAP1 may be involved in chromatin remodeling events.
• Defects or translocations in the gene encoding HSPBAP1 are associated with renal cell carcinoma 1 (RCC1), suggesting a possible role for HSPBAP1 in carcinogenesis.
• Three isoforms of HSPBAP1 exist due to alternative splicing events.
• Applications:Suitable for use in Western Blot Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.