84-4388-32　［取扱停止］HLA-A/B/C (HLA class I histocompatibility antigen, A-68 alpha Chain, Aw-68, HLA class I histocompatibility antigen, A-28 alpha Chain, MHC class I antigen A*68, HLA-A, HLAA) 100ul　360415

特徴

• Major histocompatibility complex (MHC) molecules form an integral part of the immune response system.
• They are cell-surface receptors that bind peptides and present them to T lymphocytes.
• Human leukocyte antigens (HLAs) are polymorphic members of the MHC family that are specifically involved in the presentation of antigens to the T cell receptor.
• There are two classes of HLA antigens: class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D).
• Class I molecules are expressed in nearly all cells and play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum.
• The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.
• HLA-A, -B and -C encode membrane anchored heavy chains which heterodimerize with a light chain (b-2-Microglobulin) to form MHC-I.
• Polymorphisms yield hundreds of HLA-A, -B and -C alleles.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.