HAPLN4 (Hyaluronan and proteoglycan link protein 4) is a 360aa protein encoded by the human gene HAPLN4.
HAPLN4 belongs to the HAPLN family and contains 1 Ig-like C2-type (immunoglobulin-like) domain and two Link domains.
HAPLN4 mediates the binding of complexes containing hyaluronic acid.
HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid.
HAPLN4 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization.
HAPLN4 may also be involved in the formation of extracellular matrices contributing to perineuronal nets and facilitate the understanding of a functional role of these extracellular matrices.
HAPLN4 is widely expressed with highest levels in spleen and placenta.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human HAPLN4. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa114-159 human HAPLN4.
