84-4387-69　［取扱停止］HABP2 (Hyaluronan-Binding Protein 2, Factor VII-activating Protease, Factor seven-activating Protease, FSAP, Hepatocyte Growth Factor Activator-like Protein, Plasma hyaluronan-Binding Protein, HGFAL, PHBP) 100ul　360379

特徴

• The hyaluronan-binding protein 2 (HABP2), also designated plasma hyaluronan-binding protein (PHBP) or factor VII-activating protease, belongs to the peptidase S1 family and contains three EGF-like domains, one kringle domain and one peptidase S1 domain.
• HABP2 is a heterodimer that contains a heavy chain of 50kD and a light chain of 27kD, which are linked by a disulfide bond.
• HABP2 is ubiquitously expressed and acts as a serine protease with fibrinogen and fibronectin being the major substrates.
• HABP2 has been shown to cleave the alpha-chain at multiple sites and the beta-chain between lysine53 and lysine54, but not the gamma-chain of fibrinogen.
• Overexpression of HABP2 has been shown to occur in lung adenocarcinomas and may be a useful biomarker for that type of cancer.
• Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunofluorescence: 1:50-1:200Western Blot: 1:500-1:200Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.