G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways.
G protein-coupled receptors mediate extracellular signals into intracellular signals (G protein activation).
They respond to a wide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides.
GPR proteins are usually integral seven pass membrane proteins with some conserved amino acid regions.
GPR-152 (G proteincoupled receptor 152) is a 511aa multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family.
Encoded by a gene on human chromosome 11q13.2 and mouse chromosome 19 A, GPR-152 may function as an orphan receptor.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
Specificity:Recognizes human GPR152. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to residues in human GPR152.