The Fc receptor homolog (FcRH) family of proteins are related to the classical Fc receptors (FcR) and belong to the immunoglobulin receptor superfamily.
The proteins in the FcRH family are type I transmembrane glycoproteins and consist of FcRH1-FcRH6.
The genes encoding the human FcRH proteins map to chromosome 1, near the related FCR genes.
The FcRH proteins, which are involved in immune system regulation, have immunoreceptor-tyrosine inhibitory motifs in their cytoplasmic domains.
Mutations in the gene encoding for the FcRH proteins may be associated with systemic lupus erythematosus, autoimmune thyroid disease and rheumatoid arthritis.
The FcRH genes are expressed primarily, although not exclusively, by mature B lineage cells, and may serve important regulatory roles in normal and neoplastic B cell development.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human FCRL5. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human FCRL5.
