M-ficolin, also known as ficolin-A, ficolin-1, ficolin-alpha, FCN1, FCNM or collagen/fibrinogen domain containing protein 1, is a 326aa member of the ficolin lectin family.
Characteristic of ficolin family proteins, M-ficolin contains a short N-terminal, one collagen-like domain and one fibrinogen-like domain at its C-terminal.
M-ficolin is a secreted innate immunity pattern recognition molecule predominantly expressed in peripheral blood leukocytes.
It is believed to function as a plasma protein and is known to interact with elastin, carbohydrates and corticosteroids.
M-ficolin exists as a homopolymer through intermolecular disulfide bonding and is involved in activating lectin activity via association with MASPs and specific carbohydrate ligands.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human FCN1. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to human FCN1.
