84-4384-41　［取扱停止］ELAC2 (Zinc Phosphodiesterase ELAC Protein 2, ElaC Homolog Protein 2, Heredity Prostate Cancer Protein 2, Ribonuclease Z 2, RNase Z 2, tRNA 3 Endonuclease 2, tRNase Z 2, HPC2) 50ul　360166

特徴

• The protein encoded by this gene has a C-terminal domain with tRNA 38242; processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs.
• The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest.
• Mutations in this gene result in an increased risk of prostate cancer.
• Multiple transcript variants encoding different isoforms have been found for this gene.
• Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunofluorescence: 1:50-1:200Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.