This gene encodes a member of the dishevelled (dsh) protein family.
The vertebrate dsh proteins have approximately 40%aa sequence similarity with Drosophila dsh.
This gene encodes a 90kD protein that undergoes posttranslational phosphorylation to form a 95kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins.
The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity:Recognizes human DVL2. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Recombinant protein corresponding to human DVL2.