84-4383-91　［取扱停止］DUX5 (Double Homeobox Protein 5) 100ul　360134

特徴

• The double homeobox (DUX) proteins are encoded by 3.3-kilobase repeats found throughout the human genome.
• The DUX family includes DUX1, DUX2, DUX3, DUX4 and DUX5.
• Each of these family members, excluding DUX2, contains two homeobox domains.
• DUX2 contains only one homeobox domain.
• DUX1 and DUX5 are identical to one another and they share 98% identity with DUX3 and approximately 70% identity with DUX2.
• The genes encoding DUX5 and DUX3 both contain additional start sites that result in N-terminal extended isoforms.
• The homeodomains found in DUX5 and DUX1 are similar to those found in Pax-3, Pax-7, OTX1 and OTX2.
• DUX4, also known as DUX10, is capable of forming homodimers.
• In addition, the gene encoding DUX4 maps within the D4Z4 repeat unit that has been implicated in Facioscapulohumeral muscular dystrophy (FSHD).
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.