DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly.
Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division.
DDX24 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 24) is an 859aa protein that contains one helicase C-terminal domain and one helicase ATP-binding domain.
Expressed ubiquitously with highest levels in brain and heart, DDX24 functions as an ATP-dependent RNA helicase that is subject to DNA damage-dependent phosphorylation.
Human DDX24 shares 79% sequence similarity with its mouse counterpart, suggesting a conserved role between species.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human DDX24. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human DDX24.
