Hemoglobin, myoglobin, neuroglobin, and cytoglobin belong to the globin family, porphyrin-containing proteins that function in oxygen transport and storage.
Myoglobin contributes to intracellular oxygen storage and transcellular facilitated diffusion of oxygen in skeletal and cardiac muscle.
Neuroglobin is an oxidative stress-responsive sensor for signal transduction in the brain.
Hemoglobin contributes to oxygen storage and diffusion of oxygen in blood tissue.
Cytoglobin (also designated histoglobin), is a ubiquitous protein that facilitates diffusion of oxygen through tissues and acts as a scavenger for nitric oxide or other reactive oxygen species.
It binds O2 via its heme and also has a protective function during oxidative stress.
Cytoglobin, a hexacoordinate hemoglobin, shares less than 30% identity with other human hemoglobins and is widely expressed in a wide array of tissues including fibroblasts and nerve cell populations.
Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:50-1:200Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human Cytoglobin. Species Crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu Rt
Immunogen：Recombinant protein corresponding to human Cytoglobin.
