84-4381-92　［取扱停止］COXII (Cytochrome c Oxidase Polypeptide 2, Cytochrome c Oxidase subunit 2, Cytochrome c Oxidase subunit II, Cytochrome Oxidase subunit 2, mt-Co2, Co2, COII, COX2, Cox2, COXII) 50ul　360027

特徴

• Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes.
• Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins.
• Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA).
• Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS).
• Cox-1 is constitutively expressed in most tissues and is thought to serve in general “housekeeping” functions.
• Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation.
• Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs.
• Applications:Suitable for use in Western Blot, Immunohistochemistry, Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000 Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.