Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines.
Members of the chemokine-like factor superfamily (CKLFSF) share similarities with both chemokine and transmembrane 4 superfamilies of signaling molecules.
As a member of the CKLFSF family of proteins, CMTM1 (CKLF-like MARVEL transmembrane domain-containing protein 1), also known as CKLFSF1 (Chemokine-like factor superfamily member 1), is a 169aa multi-pass membrane protein that is highly expressed in testis, therefore probably playing a role in spermatogenesis or testicular development.
CMTM1 contains a CC-chemokine motif and four transmembrane segments.
The gene encoding CMTM1 resides in a tight gene cluster on human chromosome 16 with CKLF, CMTM2, CMTM3 and CMTM4.
There are at least sixteen isoforms of CMTM1 that are produced as a result of alternative splicing events.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human CMTM1. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human CMTM1.
