The cadherins are a family of calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis.
Cadherins each contain a large extracellular domain at the N-terminal, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity.
CDH20 (cadherin 20, type 2), also known as Cdh7 or CDH7L3, is an 801aa single-pass type I membrane protein that contains five cadherin domains and belongs to the cadherin superfamily.
Expressed in both adult and fetal brain, as well as in placenta, CDH20 functions as a calcium-dependent cell adhesion protein that is thought to participate in the sorting of heterogeneous cell types.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity:Recognizes human CDH20. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa97-142 of human CDH20.