84-4380-65　CD20 (MS4A1, B-lymphocyte Antigen CD20, B-lymphocyte Surface Antigen B1, Bp35, Leukocyte Surface Antigen Leu-16, Membrane-spanning 4-Domains Subfamily A Member 1) 50ul　359956

特徴

• CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N-terminal and C-terminal.
• The cytoplasmic domain of CD20 contains multiple phosphorylation sites, leading to additional isoforms.
• CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells.
• CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1.
• CD20 is activated by the IGF-1 receptor via the alpha subunits of the heterotrimeric G proteins.
• Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription factors.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.