Eotaxin and the monocyte chemotactic proteins, MCP-1–5, form a subfamily of the C-Cr or B-chemokines, which are characterized by a set of conserved adjacent cysteines.
MCPs are produced by a variety of cells, including T lymphocytes, subsequent to their activation with cytokines such as IL-1, TNFa, and IFN-g.
In vitro studies have shown that the MCP isoforms exhibit their chemotactic effects on different subpopulations of lymphocytes.
MCP-3 has been shown to have the broadest range of influence, activating monocytes, dendritic cells, lymphocytes, NK cells, eosinophils, basophils and neutrophils.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes human CCL7. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human CCL7.
