Arylsulfatase D, also known as ARSD, is a 593aa protein that localizes to the lysosome and belongs to the sulfatase family of bone and cartilage matrix proteins.
Existing as three alternatively spliced isoforms which are expressed in liver, pancreas, kidney, heart, brain, lung and placenta, Arylsulfatase D uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition.
The gene encoding Arylsulfatase D maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
In conjunction with chromosome Y, chromosome X is responsible for sex determination.
There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
Specificity:Recognizes human ARSD. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to human ARSD.