84-4377-97　［取扱停止］APLN (Apelin, APJ Endogenous Ligand, Apelin-36, Apelin-31, Apelin-28, Apelin-13, APLN, APEL) 100ul　359800

特徴

• Apelin (APEL), an endogenous ligand for APJ, is an alternate coreceptor with CD4 for HIV-1 infection.
• This secreted protein inhibits HIV-1 entry into cells that coexpress APJ and CD4.
• By proteolytic processing of the peptide precursor, several different active peptides may be produced.
• Apelin-36, one such inotropic peptide, is being investigated as a potential plasma marker of cardiopulmonary disease.
• Apelin is highly expressed in brain, mainly in the thalamus, frontal cortex, hypothalamus and midbrain.
• Apelin is also secreted by the mammary gland into the colostrum and milk.
• Oral intake of apelin (in milk and colostrum) may be important in the modulation of the immune responses in neonates and newborns.
• Apelin has also been found to be a potent stimulator of cardiac contractility and may function in the regulation of the cardiovascular system.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.