Phosphatidic acid and lysophosphatidic acid are phospholipids involved in lipid biosynthesis and signal transduction.
LPAAT-alpha (lysophosphatidic acid acyltransferase alpha), also designated 1-acylglycerol-3-phosphate O-acyltransferase 1 (AGPAT1), catalyzes the synthesis of phosphatidic acid from lysophosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
LPAAT-alpha is a membrane-bound protein belonging to the LPAAT family.
Members of the LPAAT family have a well-known role in lipid biosynthesis and may also play a role in tumor progression.
LPAAT-alpha is widely expressed with highest expression in skeletal muscle.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human AGPAT1.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human AGPAT1.
