Cellular signal transduction pathways are initiated by the binding of external signals, such as steroids, charged-small molecules or proteins, to their respective receptors.
These signaling pathways are important in eliciting a cellular response to external stimuli.
Proteins involved in signaling pathways may have several different regulatory and/or enzymatic functions, including recruitment, activation, phosphorylation, maintenance and transport.
Mutations in these pathways may be implicated in a variety of diseases, suggesting that these intermediary proteins may be potential therapeutic targets.
Adenylosuccinate synthetase 2 (AdSS2 or AMPSase 2) is important in the AMP biosynthesis pathway (purine nucleotide biosynthesis).
It is a cytoplasmic protein that belongs to the adenylosuccinate synthetase family of proteins.
AdSS2 can form homodimers.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human ADSS. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human ADSS.
