84-4374-90　Rab9 (Ras-Related Protein Rab-9A, Member RAS Oncogene Family, RAB 9A, Rab-9, RAB-9A, RAB9A, Member RAS Oncogene Family, Ras Related Protein Rab 9A) 100ug　353014

特徴

• Ras-related protein Rab-9A, also called RAB9, is a protein that in humans is encoded by the RAB9A gene.
• This gene is mapped to Xp22.2.
• RAB9 has been localized to components of the endocytic/exocytic pathway and has been implicated in recycling of membrane receptors.
• It has been found that downregulation of RAB9A gene expression in HeLa cells induced severe cell vacuolation.
• RAB9A GTPase is directly bound by TIP47 in its active, GTP-bound conformation.
• Moreover, RAB9A increases the affinity of TIP47 for its cargo.
• This gene may involved in the transport of proteins between the endosomes and the trans Golgi network.
• RAB9A has been shown to interact with RABEPK and TIP47.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.