Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene.
The protein encoded by this gene is a cytokine important for B and T cell development.
This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor.
And it is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development.
In addition, this cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes.
Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Additional splice variants have been described but their presence in normal tissues has not been confirmed.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O.
Specificity：Recognizes mouse IL7.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to mouse IL7 expressed in E. coli. Species sequence homology: human (56.4%) and rat (87.6%)
