Fibroblast growth factor 23 or FGF23 is a protein that in humans is encoded by the FGF23 gene.
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes.
The product of this gene regulates phosphate homeostasis and transport in the kidney.
The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains.
Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR).
Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O.
Specificity：Recognizes mouse FGF23.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to mouse FGF23 expressed in E. coli. Species sequence homology: human (71.1%) and rat (94.6%)
