The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response.
As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease.
VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501aa GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver.
Induced by Th17/Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid.
Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Human Brain Tissue Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human VNN3. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to 19aa from human VNN3 at C-terminal.
