84-4373-62　TFEB, CT (TCFEB, BHLHE35, ALPHATFEB, Transcription factor EB, Class E basic helix-loop-helix protein 35, bHLHe35) 100ug　352585

特徴

• The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors (1,2).
• Recent studies have shown that lysosomal biogenesis is regulated by TFEB (3), which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1 (4).
• Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes (5).
• Applications:Suitable for use in ELISA, Immunofluorescence, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: (paraffin) 2.5ug/ml
• Optimal dilutions to be determined by the researcher.
• Positive Control:Lung Tissue Slide (Normal)
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.