84-4372-39　PTRF 1, CT (Cavin, Cavin 1, Cavin1, CGL4, FKSG13, Polymerase I and Transcript Release Factor, RNA Polymerase I and Transcript Release Factor, TTF I Interacting 12, Cavin-1) 100ug　352460

特徴

• Cavin 1-PTRF has been shown to be an essential component of caveolae.
• Cavin 1-PTRF appear to be recruited to membrane domains containing PS, cholesterol and oligomerized caveolins.
• Binding of Cavin 1-PTRF to these domains stabilizes the membrane curvature to produce the classic flask shape of caveolae.
• Disassembly of Cavin 1- PTRF releases caveolar components, including caveolins into the plasma membrane.
• Succinctly it appears that Cavin 1-PTRF regulates caveola structure and function.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.