The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2).
PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland.
ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways.
ZAC1 also acts as a transcriptional cofactor for nuclear receptors.
PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers.
It functions as a positive regulator of transcription and localizes to the nucleus.
PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Rat Brain Tissue Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human PLAGL2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to 19aa from human PLAGL2 at N-terminal.
