84-4372-02　PANX1, NT (PX1, MRS1, UNQ2529, UNQ2529/ PRO6028, Pannexin-1) 100ug　352422

特徴

• The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals.
• Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels.
• Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation.
• PANX1 is a transmembrane protein that forms a mechanosensitive ATP- permeable channel between adjacent cells and in the endoplasmic reticulum.
• PANX1 may play a role as a Ca2+-leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
• Applications:Suitable for use in Immunofluorescence, ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:Immunofluorescence: 20ug/mlWestern Blot: 1-2ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:Human Ovary Tissue Lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.