84-4371-78　NETO1, CT (BCTL1, BTCL1, Neuropilin and Tolloid-like Protein 1, Brain-Specific Transmembrane Protein Containing 2 CUB and 1 LDL-Receptor Class A Domains Protein 1) 100ug　352398

特徴

• Neuropilin and tolloid-like protein 1 (NETO1) is involved in the development and/or maintenance of neuronal circuitry.
• It is a type I transmembrane protein that is expressed in the brain and retina.
• NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted.
• It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue.
• Furthermore, as an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
• Applications:Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunofluorescence: 20ug/mlWestern Blot: 1-2ug/ml Immunohistochemistry: 2.5ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:Human Lung Tissue Lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.