84-4371-52　ME1, NT (MES, HUMNDME, NADP-dependent malic enzyme, Malic enzyme 1, NADP-ME) 100ug　352371

特徴

• ME1, also known as NADP-ME, MES or HUMNDME, may play an important role as a housekeeping protein within the cell (1).
• ME1 is a 572aa cytoplasmic protein that belongs to the malic enzyme family (2).
• It is expressed ubiquitously with highest expression in liver and white adipose tissue.
• ME1 functions as an NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (3).
• The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles (3,4).
• ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet (5).
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1-2ug/mlImmunohistochemistry (paraffin): 5ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:293 Cell Lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.