84-4371-50 MAP1LC3B, NT (LC3B, Microtubule-associated protein 1 light chain 3 beta, ATG8F, MAP1LC3B-a, MAP1A/1BLC3, MAP1ALC3, Autophagy-related protein LC3 B) 100ug 352369
特徴
- Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1).
- MAP1LC3B belongs to the MAP1 LC3 family and it includes 3 different light chains, LC1, LC2 and LC3 (2).
- MAP1LC3B is involved in formation of autophagosomal vacuoles (autophagosomes) (3).
- It is most abundant in heart, brain, skeletal muscle and testis.
- MAP1LC3B is essential for autophagy and associated to the autophagosome membranes after processing (4).
- Applications:Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Immunofluorescence: 20ug/mL
- Western Blot: 1-2ug/ml
- Immunohistochemistry (paraffin): 5ug/mLOptimal dilutions to be determined by the researcher.
- Positive Control:Human Brain Tissue Lysate
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ug
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, 0.02% sodium azide.
- Specificity：Recognizes human MAP1LC3B. Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：E IF IHC WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to 18aa near the N-terminal of human MAP1LC3B.
- Shelf Life：6months
- Swiss Prot Number：Q9GZQ8
- EU Commodity Code：30021010
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