GLIS2, also known as neuronal Krueppel-like, is a 524aa protein that belongs to the GLI C2H2-type zinc-finger protein family.
GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation.
GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta.
Mutations of GLIS2 have been suggested to be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1-2ug/mlImmunohistochemistry (Paraffin): 5ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:K562 Cell Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography
Form：Supplied as a liquid in PBS, 0.02% sodium azide
Specificity：Recognizes human GLIS2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Peptide corresponding to 18aa near the center of human GLIS2. Epitope: aa260-310
