COMMD7 (COMM domain-containing protein 7) plays a role in the regulation NF-kappaB (1).
It associates with the NF-kB complex and suppresses its transcriptional activity (2).
COMMD7 contains 1 COMM domain and widely expressed with highest expression in lung (3).
COMMD7 is a newly identified gene overexpressed in hepatocellular carcinoma (HCC) (4).
COMMD7 is associated with tumor invasion and poor prognosis by NF-kappaB signaling pathway (4).
Applications:Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 20ug/mlWestern Blot: 1-2ug/mlImmunohistochemistry: 5ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Mouse Spleen Tissue Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human COMMD7. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Peptide corresponding to 19aa from human COMMD7.
