84-4369-31　BCAR3, NT (NSP2, SH2D3B, NSP2, UNQ271/PRO308, Breast Cancer Anti-estrogen Resistance Protein 3, Novel SH2-Containing Protein 2) 100ug　352139

特徴

• Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance.
• It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48.
• BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility.
• BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling.
• Applications:Suitable for use in Immunofluorescence, ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:Immunofluorescence: 20ug/mlWestern Blot: 1-2ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:HeLa Cell Lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.