84-4368-02　Pax2, CT (Paired box protein Pax-2, Paired box 2) 100ug　350774

特徴

• Paired box gene 2, also known as PAX2, is a protein which in humans is encoded by the PAX2 gene.
• This gene is mapped to 10q24.
• PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd.
• The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain.
• PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1.
• Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.
• Alternative splicing of this gene results in multiple transcript variants.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlImmunohistochemistry (paraffin): 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
• Reconstitute with sterile dH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.