84-4367-92　MLH1, CT (DNA mismatch repair protein Mlh1, MutL homolog 1) 100ug　350742

特徴

• MutL homolog 1, colon cancer, nonpolyposis type 2 (E.
• coli) is a protein that in humans is encoded by the MLH1 gene located on Chromosome 3.
• This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC).
• It is a human homolog of the E.
• coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC.
• Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Additional transcript variants have been described, but their full-length natures have not been determined.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.