84-4367-66　ELAVL4, NT (ELAV like neuron-specific RNA binding protein 4, ELAV-like Protein 4, Hu-antigen D, HuD, Paraneoplastic Encephalomyelitis Antigen HuD, HUD, PNEM) 100ug　350601

特徴

• HuD, otherwise known as ELAV-like protein 4 or PNEM, is a protein that in humans is encoded by the ELAVL4 gene.
• This human gene is located at 1p34 by in situ hybridization.
• The HuD/ELAVL4 protein is an RNA-binding protein.
• ELAVL4 has specificity for 3-prime uridylate-rich untranslated regions of growth factor mRNAs.
• And HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs.
• As a result of this interaction the, half-life of the transcript is increased.
• Also, HuD is important in neurons during brain development and plasticity.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlImmunohistochemistry (paraffin): 0.5-1ug/ml Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.