84-4367-42 NLRC4, CT (CARD12, NLR family CARD domain-containing protein 4) 100ug 350757
特徴
- NLR family CARD domain-containing protein 4, also known as CARD12, is a protein that in humans is encoded by the NLRC4 gene.
- It is mapped to 2p22.3.
- This gene encodes a member of the caspase recruitment domain-containing NLR family.
- Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses.
- Mutations in this gene result in autoinflammation with infantile enterocolitis.
- Alternative splicing results in multiple transcript variants.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilutions:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
- Reconstitute with sterile dH2O.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size：100ug
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O.
- Specificity：Recognizes human NLRC4. Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Synthetic peptide corresponding to aa838-874 KILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDR at the C-terminal of human NLRC4
- Shelf Life：1year
- Swiss Prot Number：Q9NPP4
- EU Commodity Code：30021010
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