84-4367-20　Kv1.2, CT (KCNA2, Potassium voltage-gated channel subfamily A member 2) 100ug　350709

特徴

• Potassium voltage-gated channel subfamily A member 2, also known as Kv1.2, is a protein that in humans is encoded by the KCNA2 gene.
• Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints.
• Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
• Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s).
• This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily.
• This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment.
• It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential.
• The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/ml Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
• Reconstitute with sterile dH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.