84-4366-82　Lamin B1 (LMNB1, LMN2, LMNB) 100ug　350712

特徴

• Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene.
• The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane.
• The lamin family of proteins make up the matrix and are highly conserved in evolution.
• During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated.
• Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.
• Vertebrate lamins consist of two types, A and B.
• This gene encodes one of the two B type proteins, B1.
• Applications:Suitable for use in ELISA, Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlImmunohistochemistry (paraffin): 0.5-1ug/ml Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
• Reconstitute with sterile dH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.