84-4366-28　Apg7, CT (ATG7, GSA7, Ubiquitin-like modifier-activating enzyme ATG7, APG7L, Ubiquitin-Activating Enzyme E1-like Protein, Autophagy related 7) 100ug　350547

特徴

• Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene.
• It is mapped to 3p25.3.
• This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7.
• In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes.
• The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
• ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy.
• It is found that when nutrients are limited, ATG7 can regulate p53-dependent cell cycle and cell death pathways.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
• Reconstitute with sterile dH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.