84-4366-10　Profilin 1, CT (PFN1) 100ug　350796

特徴

• Profilin-1 is a protein that in humans is encoded by the PFN1 gene.
• The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family.
• PFN1 is mapped to 17p13.2.
• At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
• This gene is a 140aa protein and major growth regulator of filamentous (F)-actin through its binding of monomeric (G)-actin.
• It is thought to regulate actin polymerization in response to extracellular signals.
• Deletion of this gene is associated with Miller-Dieker syndrome.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.