84-4361-09 p70 S6 Kinase, phosphorylated (Ser424) 100ul 327301
特徴
- Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens.
- Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.
- Satoru Eguchi et al.
- (1999) J Biol Chem, Vol.
- 274: 36843-36851 Papst PJ, et al.
- (1998) J Biol Chem.
- 273(24):15077-84.
- Ulrike Krause et al.
- (2002) Eur.
- J.
- Biochem.
- 269: 3751-3759 c Le, X.F, et al.
- (2003) Oncogene 22: 484
- Applications:Suitable for use in Immunofluorescence and Western Blot.
- Other applications not tested.
- Recommended Dilution:Immunofluorescence: 1:100-1:200Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：IF WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to the sequence around phosphorylation site of serine 424 (P-V-S(p)-P-V) derived from human p70 S6 Kinase.
- Shelf Life：1year
- Swiss Prot Number：P23443
- EU Commodity Code：30021010
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