84-4360-46 MLC2 (Phospho-Tyr118) 100ul 324097
特徴
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation.
Implicated in cytokinesis, receptor capping, and cell locomotion.
1) Xia, Y.
et al.
c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis.
Mol.
Cell 25, 219–232 (2007).
2)Vander Heiden, M.
G.
et al.
Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
Science 329, 1492–1499 (2010).
3) Fang, D.
et al.
Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity.
J.
Biol.
Chem.
282, 11221–11229 (2007).
WB IF Recommended dilution: Western blotting:1:500~1:1000
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Peptide corresponding to the sequence around phosphorylation site of tyrosine 118 (A-D-Y(p)-V-R) derived from human MLC2.
Shelf Life：1year
Swiss Prot Number：P24844
EU Commodity Code：30021010
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